Investigation of rheological properties of hydroxyapatite and fluorapatite in colloidal state

E.A. Bogdanova, V.M. Skachkov

Institute of Solid State Chemistry of the Ural Branch of RAS

DOI: 10.26456/pcascnn/2020.12.525

Original article

Abstract: The article discusses the possibility of practical application of a suspension of hydroxyapatite and fluorapatite as components of medicines, pharmaceutical compositions, and biomaterials. Their viscosity, density and degree of dispersion were estimated by using the physical and chemical analysis methods. The concentration intervals in which the studied systems have the properties necessary for creating pharmaceutical compositions and biomaterials are determined. The biological activity of apatites largely depends on the degree of dispersion and manifests itself the more, the smaller the size of their particles, and the obtained in this work nanoparticles of hydroxyapatite and fluorapatite in suspensions have a particle size of the order of less than 100 nm, and, consequently, their rheological properties will be most fully manifested.

Keywords: hydroxyapatite, fluorapatite, rheological properties, biomaterials

• Ekaterina A. Bogdanova – Ph. D., Senior Researcher, Laboratory of Heterogeneous Processes, Institute of Solid State Chemistry of the Ural Branch of RAS
• Vladimir M. Skachkov – Ph. D., Senior Researcher, Laboratory of Heterogeneous Processes, Institute of Solid State Chemistry of the Ural Branch of RAS

Reference:

Bogdanova, E.A. Investigation of rheological properties of hydroxyapatite and fluorapatite in colloidal state / E.A. Bogdanova, V.M. Skachkov // Physical and chemical aspects of the study of clusters, nanostructures and nanomaterials. — 2020. — I. 12. — P. 525-534. DOI: 10.26456/pcascnn/2020.12.525. (In Russian).

Full article (in Russian): download PDF file

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