Physical and chemical aspects of the study of clusters, nanostructures and nanomaterials
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The effect of the mixing rate of the reaction mixture on the dispersed characteristics of the nanoemulsion of fat-soluble vitamin E (alpha-tocopherol acetate)

A.V. Blinov, K.S. Slyadneva, A.A. Gvozdenko, A.B. Golik, M.A. Taravanov, E.D. Nazaretova

North Caucasus Federal University

DOI: 10.26456/pcascnn/2022.14.754

Original article

Abstract: The article presents the results of a study of the effect of the mixing rate on the dispersed characteristics of nanoemulsions of the fat-soluble vitamin E (alpha-tocopherol acetate). The mixing speed was varied in the range of 3000-22500 rpm. The average hydrodynamic radius of the micelles of fat-soluble vitamin E was considered as an output parameter, which was determined by the method of the dynamic light scattering. It was found that as a result of synthesis, micelles of the fat-soluble vitamin E emulsions are formed, having a monomodal size distribution. The smallest average hydrodynamic radius of the particles was 22 nm. It was found that an increase in the mixing speed from 3000 to 22500 rpm causes a decrease in the average hydrodynamic radius of micelles. The greatest changes are observed at τ = 30 s: a decrease in the average hydrodynamic radius of micelles Rm occurs by 3,3 times (from 210 to 63 nm). It is important to note that an increase in other synthesis parameters also leads to a decrease in the value of the average hydrodynamic radius of micelles of the vitamin E nanoemulsions. By v = 22500 rpm an increase in the mixing time τ from 30 s to 270 s leads to a decrease in Rm by 19 nm (from 63 to 44 nm).

Keywords: fat-soluble vitamin E, nanoemulsion, hydrodynamic radius, mixing speed

  • Andrey V. Blinov – Ph. D., Assistant professor, Department of Physics and Technology of Nanostructures and Materials, Faculty of Physics and Technology, North Caucasus Federal University
  • Kristina S. Slyadneva – 3rd year student, Department of Physics and Technology of Nanostructures and Materials, Faculty of Physics and Technology, North Caucasus Federal University
  • Alexey A. Gvozdenko – Assistant, Department of Physics and Technology of Nanostructures and Materials, Faculty of Physics and Technology, North Caucasus Federal University
  • Alexey B. Golik – Assistant, Department of Physics and Technology of Nanostructures and Materials, Faculty of Physics and Technology, North Caucasus Federal University
  • Maxim A. Taravanov – 2nd year student, Department of Physics and Technology of Nanostructures and Materials, Faculty of Physics and Technology, North Caucasus Federal University
  • Ekaterina D. Nazaretova – student, Specialized Educational and Scientific Center, North Caucasus Federal University

Reference:

Blinov, A.V. The effect of the mixing rate of the reaction mixture on the dispersed characteristics of the nanoemulsion of fat-soluble vitamin E (alpha-tocopherol acetate) / A.V. Blinov, K.S. Slyadneva, A.A. Gvozdenko, A.B. Golik, M.A. Taravanov, E.D. Nazaretova // Physical and chemical aspects of the study of clusters, nanostructures and nanomaterials. — 2022. — I. 14. — P. 754-762. DOI: 10.26456/pcascnn/2022.14.754. (In Russian).

Full article (in Russian): download PDF file

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