The use of SiO2 – MnO2 nanopowders for targeted drug delivery
O.A. Zlygosteva, S.Yu. Sokovnin, V.G. Il’ves
Ural Federal University named after the First President of Russia B. N. Yeltsin
Institute of Electrophysics of the Ural Branch of RAS
Abstract: Application of manganese-doped mesoporous silica nanopowders SiO2 – MnO2 for targeted drug delivery was researched. It has been established that an increase in sonicated time leads to changes in the NP structure. The produced nanopowders have a high loading capacity 0,09 mg of Amoxicillin per mg of nanopowder, 0,075 mg of Doxorubicin per mg of nanopowder that is five times higher than the loading capacity of chemically synthesized nanopowders.
Keywords: mesoporous silica nanopowder, dopant manganese dioxide, targeted drug delivery.
Zlygosteva, O.A. The use of SiO2 – MnO2 nanopowders for targeted drug delivery / O.A. Zlygosteva, S.Yu. Sokovnin, V.G. Il’ves // Physical and chemical aspects of the study of clusters, nanostructures and nanomaterials: Interuniversity collection of proceedings / Ed. by V.M. Samsonov, N.Yu. Sdobnyakov. – Tver: TSU, 2018. – I. 10. – P. 262-269.
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