Properties evaluation of mesoporous silica nanopowders doped with manganese dioxide produced by a pulsed electron beam evaporation for biomedical applications
O.A. Zlygosteva1, S.Yu. Sokovnin1,2, V.G. Il’ves2
1Ural Federal University named after the first President of Russia B.N.Yeltsin
2Institute of Electrophysics of the Ural Division of RAS
Abstract: The researched manganese-doped mesoporous silica nanopowder (NP) SiO2 – MnO2 with different dopant concentrations has been carried out by a physical method of the electron beam evaporation in vacuum on NANOBIM-2 installation. Basic analyses of NP demonstrate high porosity and ferromagnetic properties. Cytotoxicity experiments on cells showed that NP exerted low toxicity. The loading experiments using a spectrophotometer demonstrate interaction of the Amoxicillin drug with the surface of NP.
Keywords: mesoporous silica nanopowders doped with manganese dioxide, active targeted drug delivery.
Zlygosteva, O.A. Properties evaluation of mesoporous silica nanopowders doped with manganese dioxide produced by a pulsed electron beam evaporation for biomedical applications / O.A. Zlygosteva, S.Yu. Sokovnin, V.G. Il’ves // Physical and chemical aspects of the study of clusters, nanostructures and nanomaterials: Interuniversity collection of proceedings / Ed. by V.M. Samsonov, N.Yu. Sdobnyakov. – Tver: TSU, 2017. – I. 9. – P. 199-204.
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